Northern Superchargers and Oval Invincibles are guaranteed a top-three finish after the Superchargers won the encounter between the two teams in the earlier match at Headingley.
Both teams have 20 points and only Trent Rockets, currently on 16 with two games to play, can match or overtake them.
After Harry Brook’s first half-century of this year’s Hundred and Zak Crawley’s rapid 49 helped Superchargers set a target of 199, Will Jacks’ 11-ball 25 gave the Invincibles a brisk start in their chase.
But Jacob Duffy halted his charge inside the powerplay before Tom Lawes struck twice, dismissing Tawanda Muyeye and the in-form Jordan Cox – who came into the match on the back of three consecutive half-centuries.
When Sam Curran edged Matthew Potts to wicketkeeper Michael Pepper, the Invincibles were reeling at 115-4.
But Donovan Ferreira gave them some hope by hitting three fours and three sixes from seven deliveries before falling for a 15-ball 41 – Duffy ending the chance of a dramatic comeback to set the Superchargers on their way to a crucial win.
Earlier, openers Crawley and Dawid Malan gave the hosts a flying start after being sent in to bat by Invincibles skipper Sam Billings.
Crawley set the tone, helping them race to 49 without loss by the end of the powerplay, before falling just one run short of a fifty.
Captain Brook consolidated the Superchargers’ innings with a 27-ball 56 that included five sixes and three fours, before David Miller added the finishing touches, launching Tom Curran for three consecutive sixes in the final set to take them to 198-4.
Two-time defending champions Invincibles will host London Spirit in their final game on Monday, while Superchargers take on Manchester Originals the following day, live on the BBC.